Uber Uniques in Season 14 remain the ultimate gear chase, but farming them efficiently requires understanding which boss to target for which item. Each Tormented Boss has a weighted drop pool that favors specific Mythic types. Running the wrong boss for your target item can triple the time needed to find it. This guide maps the complete drop pool for each boss with material cost analysis and group rotation efficiency strategies.
Duriel is the most versatile boss for Mythic farming. His drop pool covers all Mythic types, but the weighting favors weapons and rings. Data from 500 Duriel kills shows a 2.1 percent Mythic drop rate with weapon types appearing 40 percent more often than armor types. Andariel has a similar drop rate but skews toward helms and amulets. The material cost for Duriel is higher because you need to farm both Grigoire and Varshan materials first. Each Duriel summon costs 2 Mucus Eggs and 2 Shards of Agony. In a full group rotation of 4 players contributing equally, each player gets 4 attempts worth of drops for the cost of 1 attempt. This 4x efficiency multiplier makes group rotations the single most important strategy for Mythic farming.
Material cost per boss is the hidden factor. Lord Zir costs 9 Exquisite Blood per summon. Exquisite Blood comes from World Boss kills and Legion events, which are time-gated. You can farm roughly 30 Exquisite Blood per hour from a focused World Boss and Legion rotation. The Beast in Ice costs 9 Distilled Fear per summon, which requires farming Tier 50-plus Nightmare Dungeons. Distilled Fear drops at roughly 3 per 30-minute Nightmare Dungeon run, making the Beast the most material-expensive boss per attempt. Grigoire costs 5 Living Steel from Helltide chests, making him the cheapest boss to summon at roughly 10 minutes of farming per attempt. The Diablo 4 war plans best build for boss farming allocates points to both the material generation branch and the boss-specific damage branches. Getting the War Plan allocation right before a farming session increases your clear speed by 20 percent and your material generation by 15 percent.
Mythic drop rate optimization through War Plans. The War Plan system includes a branch that increases unique drop rates from Tormented Bosses by 10 percent at maximum allocation. This is one of the most valuable War Plan investments for endgame players. The node is deep in the activity-specific tree, requiring 12 points to reach. Combined with the boss damage nodes, a fully allocated bossing War Plan setup requires approximately 30 points. The Diablo 4 war plans guide has a dedicated section for boss farming allocation that prioritizes the unique drop chance nodes over generic damage nodes for maximum Mythic acquisition rate. Switching to your farming War Plans after the boss rotation restores your material generation efficiency.

Death Toll the new boss: Season 14 introduces the Death Toll boss, which requires Pandemonium Fragments from the seasonal activity War Plan tree. His drop pool favors the new seasonal Mythic items. The Death Toll is worth farming early in your boss rotation because the seasonal Mythic items are tradable and sell for premium prices on the first week of release. Focus your first 10 Death Toll kills on acquiring seasonal Mythics for potential profit before farming for your own build. The War Plan allocation for Death Toll requires 8 points in the seasonal branch, which should be prioritized before any other boss-specific nodes.